SCHEMBL868205

SCHEMBL868205

C=C(C)COC(=O)/C=C/C(=O)OCC(=C)C

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.43
ATM Q13315 1/20 0.43
ALDH1A1 P00352 2/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
MAPT P10636 7/20 0.36
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
LMNA P02545 2/20 0.35
THRB P10828 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
MDM4 O15151 1/20 0.33
MDM2 Q00987 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10688847 1.00 HCAR2 (0.43) HCAR2ATMALDH1A1KEAP1NFE2L2
SCHEMBL868207 0.91 HCAR2 (0.57) HCAR2ATMALDH1A1MAPTTSHR
SCHEMBL10688851 0.91 HCAR2 (0.57) HCAR2ATMALDH1A1MAPTTSHR
SCHEMBL868206 0.91 HCAR2 (0.57) HCAR2ATMALDH1A1MAPTTSHR
SCHEMBL30475127 0.91 HCAR2 (0.57) HCAR2ATMALDH1A1MAPTLMNA
SCHEMBL4456361 0.91 HCAR2 (0.54) HCAR2ATMALDH1A1KEAP1NFE2L2
SCHEMBL4456360 0.91 HCAR2 (0.54) HCAR2ATMALDH1A1KEAP1NFE2L2
SCHEMBL14717611 0.83 ALDH1A1 (0.33) HCAR2ATMALDH1A1TSHR
SCHEMBL4672602 0.83
SCHEMBL253351 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131396-B1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2021-09-15 EP claimed
US-10039281-B2 Pesticidal tape for controlling crawling pests BASF SE (DE) 2018-08-07 US claimed
US-20170238538-A9 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-08-24 US claimed
EP-2451283-B1 INSECTICIDE-COATED SUBSTRATE FOR PROTECTING HUMANS AND PETS BASF SE (DE) 2017-06-21 EP claimed
EP-3131396-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-02-22 EP claimed
US-20170035047-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-02-09 US claimed
WO-2015158826-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2015-10-22 WO claimed
US-20120114726-A1 INSECTICIDE-COATED SUBSTRATE FOR PROTECTING HUMANS AND PETS BASF SE (DE) 2012-05-10 US claimed
EP-3131396-B1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2021-09-15 EP disclosed
US-10039281-B2 Pesticidal tape for controlling crawling pests BASF SE (DE) 2018-08-07 US disclosed
US-20170238538-A9 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-08-24 US disclosed
EP-3131396-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-02-22 EP disclosed
US-20170035047-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-02-09 US disclosed
US-9464456-B2 System for protecting stored goods BASF SE (DE) 2016-10-11 US disclosed
EP-0376751-A1 Polymerizable cyclic urea derivatives and polymers having a pendant urea NIPPON PAINT CO., LTD. (JP) 1990-07-04 EP disclosed
US-4914225-A MOLDING MATERIALS, COATINGS, ADHESIVES NIPPON PAINT CO., LTD. (JP) 1990-04-03 US disclosed
US-4816537-A COATINGS, AUTOMOBILES NIPPON PAINT CO., LTD. (JP) 1989-03-28 US disclosed
EP-0243207-A2 Alpha-alkylacrylamide derivatives and their polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed
EP-0243208-A2 Acrylamide derivatives and their polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed
EP-0243160-A2 Blocked isocyanatocarbonyl group-containing polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170035047-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS ACHE, AS3MT, DDT HCAR2 2830/4885ATM 3197/4885ALDH1A1 549/4885
US-10039281-B2 Pesticidal tape for controlling crawling pests ACHE, AS3MT, DDT HCAR2 2830/4885ATM 3197/4885ALDH1A1 549/4885
US-20170238538-A9 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS ACHE, AS3MT, DDT HCAR2 2830/4885ATM 3197/4885ALDH1A1 549/4885
US-20120114726-A1 INSECTICIDE-COATED SUBSTRATE FOR PROTECTING HUMANS AND PETS DDT, PIR, CYP3A43 HCAR2 542/4885ATM 2339/4885ALDH1A1 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.