Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GRK6 | P43250 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461356 | 0.92 | PLA2G4B (0.51) | PLA2G4BKDM4EALDH1A1MAPTHSP90AA1 | |
| SCHEMBL4462764 | 0.92 | PLA2G4B (0.46) | KMT2APLA2G4BKDM4ELMNAHTT | |
| SCHEMBL4462759 | 0.92 | PLA2G4B (0.46) | KMT2APLA2G4BKDM4ELMNAHTT | |
| SCHEMBL4465726 | 0.89 | KMT2A (0.46) | POLBKMT2AKDM4ELMNAHTT | |
| SCHEMBL4461920 | 0.87 | FEN1 (0.55) | KMT2AKDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL4461928 | 0.87 | FEN1 (0.55) | KMT2AKDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL4458670 | 0.86 | MAPT (0.51) | KMT2AKDM4ELMNAHTTL3MBTL1 | |
| Benzoic Acid SCHEMBL4470207 | 0.85 | ALDH1A1 (0.54) | POLBKMT2AKDM4ELMNAHTT | |
| Benzoic Acid SCHEMBL4470216 | 0.85 | ALDH1A1 (0.54) | POLBKMT2AKDM4ELMNAHTT | |
| 4-Nitrobenzoic Acid SCHEMBL4454979 | 0.84 | KDR (0.54) | KMT2AKDM4ELMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |