Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 6/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | XPO1 | O14980 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | CDC14B | O60729 | 1/20 | 0.35 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26375286 | 0.80 | ELANE (0.42) | NOTUMELANEHRH4PTGESALDH1A1 | |
| SCHEMBL4468051 | 0.76 | ELANE (0.64) | ELANEXPO1C1R | |
| SCHEMBL1096064 | 0.71 | ELANE (0.66) | NOTUMELANEALDH1A1PARP1KDM4E | |
| SCHEMBL16213278 | 0.70 | TDP1 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15842270 | 0.69 | HSD17B3 (0.50) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3533214 | 0.68 | KDM4E (0.57) | ELANEALDH1A1PARP1KDM4EMEN1 | |
| SCHEMBL24820223 | 0.68 | ELANE (0.43) | NOTUMELANEALDH1A1KDM4EKMT2A | |
| SCHEMBL28217076 | 0.68 | HRH4 (0.35) | NOTUMELANEHRH4PARP1MEN1 | |
| SCHEMBL20346652 | 0.68 | TYMS (0.39) | NOTUMHRH4ALDH1A1PARP1KDM4E | |
| SCHEMBL20346729 | 0.67 | ELANE (0.40) | ELANEALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131664-A1 | Method for Producing 4(3H)-Quinazolinone Derivative | MSD K.K. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1903040-A1 | METHOD FOR PRODUCING 4(3H)-QUINAZOLINONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-03-26 | — | — | EP | disclosed |