SCHEMBL26375286

SCHEMBL26375286

Cc1nc2c(C(F)(F)F)cccc2o1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.42
PTGES O14684 2/20 0.41
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HRH4 Q9H3N8 2/20 0.39
NOTUM Q6P988 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
HSD11B1 P28845 2/20 0.36
PARP1 P09874 1/20 0.36
GRM2 Q14416 1/20 0.35
MPL P40238 1/20 0.35
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12607757 0.85 ELANE (0.42) ELANEPTGESALDH1A1KDM4EMEN1
SCHEMBL19914338 0.80 HRH4 (0.38) ELANEPTGESALDH1A1MEN1KMT2A
SCHEMBL31391540 0.80 HRH4 (0.38) ELANEALDH1A1MEN1KMT2AHRH4
SCHEMBL30237792 0.80 HRH4 (0.43) ELANEALDH1A1MEN1KMT2AHRH4
SCHEMBL19914341 0.80 HRH4 (0.38) ELANEALDH1A1MEN1KMT2AHRH4
SCHEMBL4456654 0.80 NOTUM (0.40) ELANEPTGESALDH1A1KDM4EMEN1
Hydrochloric Acid SCHEMBL19899565 0.79 HRH4 (0.42) ALDH1A1MEN1KMT2AHRH4NOTUM
SCHEMBL23932494 0.77 HRH4 (0.36) ELANEPTGESALDH1A1KDM4EHRH4
SCHEMBL30041966 0.77 HRH4 (0.36) ELANEPTGESALDH1A1KDM4EHRH4
SCHEMBL24910307 0.77 HRH4 (0.36) ELANEALDH1A1HRH4NOTUML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 ELANE 2870/4885PTGES 3954/4885ALDH1A1 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.