Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741086 | 0.92 | FFAR1 (0.51) | FFAR1FFAR4MMP2MMP12CA12 | |
| SCHEMBL10741087 | 0.92 | FFAR1 (0.51) | FFAR1FFAR4MMP2MMP12CA12 | |
| SCHEMBL2853680 | 0.89 | FFAR1 (0.55) | FFAR1FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL2853683 | 0.89 | FFAR1 (0.55) | FFAR1FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL14539007 | 0.83 | S1PR1 (0.52) | HDAC3HDAC1HDAC2HDAC8CA12 | |
| SCHEMBL13513418 | 0.83 | FFAR1 (0.46) | FFAR1FFAR4HDAC1MMP2MMP12 | |
| SCHEMBL19867116 | 0.82 | CA12 (0.54) | FFAR1CA12CA1CA2TYR | |
| SCHEMBL6716853 | 0.81 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL2850993 | 0.80 | FFAR1 (0.52) | FFAR1FFAR4HDAC3HDAC1HDAC2 | |
| SCHEMBL2850995 | 0.80 | FFAR1 (0.52) | FFAR1FFAR4HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | disclosed |
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | disclosed |
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105913-A1 | Alkynyl aryl carboxamides | ECHS1, IRS1, HCCS | FFAR1 91/4885FFAR4 218/4885HDAC3 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.