Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalamide SCHEMBL31306314 | 0.88 | TSHR (0.54) | KMT2APARP10ALDH1A1TDP1L3MBTL1 | |
| Adipic Acid SCHEMBL3804252 | 0.84 | KMT2A (0.61) | KMT2AALDH1A1TDP1L3MBTL1TSHR | |
| Adipic Acid SCHEMBL27731397 | 0.84 | KMT2A (0.61) | KMT2AALDH1A1TDP1L3MBTL1TSHR | |
| Sebacic Acid SCHEMBL28279615 | 0.82 | TSHR (0.60) | KMT2AALDH1A1TDP1L3MBTL1TSHR | |
| Benzene SCHEMBL28164652 | 0.82 | PARP1 (0.64) | KMT2APARP10ALDH1A1SMN1; SMN2TDP1 | |
| Azelaic Acid SCHEMBL3807504 | 0.82 | TSHR (0.60) | KMT2AALDH1A1TDP1L3MBTL1TSHR | |
| P-Xylene SCHEMBL36101 | 0.82 | TSHR (0.60) | KMT2AALDH1A1TDP1L3MBTL1TSHR | |
| Sebacic Acid SCHEMBL36102 | 0.82 | TSHR (0.60) | KMT2AALDH1A1TDP1L3MBTL1TSHR | |
| Terephthalamide SCHEMBL17907469 | 0.82 | ALDH1A1 (0.62) | KMT2APARP10ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL76475 | 0.82 | ALDH1A1 (0.62) | KMT2APARP10ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240235-A1 | MEDICAL CATHETER TUBE AND PROCESS FOR PRODUCING THE SAME | KANEKA CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090012500-A1 | Medical Catheter Tube and Method of Producing the Same | KANEKA CORPORATION (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1847288-A1 | MEDICAL CATHETER TUBE AND METHOD OF PRODUCING THE SAME | Kaneka Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |
| EP-1825879-A1 | MEDICAL CATHETER TUBE AND PROCESS FOR PRODUCING THE SAME | Kaneka Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| EP-1787674-A1 | CATHETER TUBE FOR MEDICAL TREATMENT AND METHOD OF MANUFACTURING THE SAME | Kaneka Corporation (JP) | 2007-05-23 | — | — | EP | disclosed |