SCHEMBL4456975

SCHEMBL4456975

C[Si](C)=[Zr](Cl)(Cl)(C1C(c2ccco2)=Cc2ccccc21)C1C(c2ccco2)=Cc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5951060 0.81 HTR1A (0.30)
SCHEMBL5951172 0.79 SMARCA2 (0.32) KMT2A
SCHEMBL3734169 0.79
Hydrochloric Acid SCHEMBL4456977 0.78 CHRM2 (0.31) KMT2ACHRM2CHRM4CHRM5CHRM1
SCHEMBL5950994 0.77
SCHEMBL4459251 0.76 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6056232 0.75
SCHEMBL7935730 0.74
SCHEMBL5951015 0.74
SCHEMBL339225 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090069171-A1 Catalysts for olefin polymerization, process for production of the catalysts, and method for preservation thereof JAPAN POLYPROPYLENE CORPORATION (JP) 2009-03-12 US disclosed
EP-1066300-B1 METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION CHISSO CORP (JP) 2003-08-20 EP disclosed
US-6326493-B1 COORDINATION CATALYST CHISSO CORPORATION (JP) 2001-12-04 US disclosed
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed
US-6169051-B1 CONSISTING OF COMPLEX COMPOUNDS WHEREIN A CYCLOALKADIENYL RING-CONTAINING MULTIDENTATE COMPOUND SUBSTITUTED ON THE RING BY A HETEROAROMATIC GROUP CONTAINING AN OXYGEN, A SULFUR OR A NITROGEN ATOM IS COORDINATED TO A GROUP VIB TRANSITION METAL CHISSO CORPORATION (JP) 2001-01-02 US disclosed