SCHEMBL4456981

SCHEMBL4456981

O=C(/C=C/c1ccccc1)N1CC1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.89
MEN1 O00255 1/20 0.89
POLB P06746 1/20 0.83
RAB9A P51151 3/20 0.77
ME2 P23368 1/20 0.71
ME1 P48163 1/20 0.71
ME3 Q16798 1/20 0.71
AR P10275 1/20 0.69
SMN1; SMN2 Q16637 4/20 0.68
GPR183 P32249 3/20 0.65
LMNA P02545 3/20 0.65
GAA P10253 2/20 0.65
NPC1 O15118 2/20 0.63
MAPT P10636 3/20 0.63
ALDH1A1 P00352 2/20 0.63
PLIN1 O60240 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2D6 P10635 1/20 0.63
CYP2C9 P11712 1/20 0.63
F3 P13726 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16599447 1.00 KMT2A (0.89) KMT2AMEN1POLBRAB9AME2
SCHEMBL16599448 1.00 KMT2A (0.89) KMT2AMEN1POLBRAB9AME2
SCHEMBL16333074 0.94 KMT2A (0.81) KMT2AMEN1POLBRAB9AME2
SCHEMBL16333072 0.94 KMT2A (0.81) KMT2AMEN1POLBRAB9AME2
SCHEMBL692258 0.92 MEN1 (0.90) KMT2AMEN1POLBRAB9AME2
SCHEMBL692257 0.92 MEN1 (0.90) KMT2AMEN1POLBRAB9AME2
SCHEMBL14610112 0.91 POLB (1.00) KMT2AMEN1POLBRAB9AME2
SCHEMBL5692929 0.91 KMT2A (0.76) KMT2AMEN1POLBRAB9AME2
SCHEMBL5692934 0.91 KMT2A (0.76) KMT2AMEN1POLBRAB9AME2
SCHEMBL692605 0.91 MEN1 (0.87) KMT2AMEN1POLBRAB9AME2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7514507-B2 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-04-07 US disclosed
US-20070142611-A1 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-21 US disclosed