SCHEMBL692258

SCHEMBL692258

O=C(C=Cc1ccccc1)N1CCCC1

nearest known ligand 0.90

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.90
KMT2A Q03164 3/20 0.90
RAB9A P51151 5/20 0.73
POLB P06746 2/20 0.73
SMN1; SMN2 Q16637 6/20 0.63
MAPT P10636 5/20 0.63
NPC1 O15118 4/20 0.63
HPGD P15428 2/20 0.63
ME2 P23368 1/20 0.63
ME1 P48163 1/20 0.63
ME3 Q16798 1/20 0.63
ALDH1A1 P00352 6/20 0.63
LMNA P02545 3/20 0.63
TP53 P04637 1/20 0.63
AR P10275 1/20 0.61
GAA P10253 1/20 0.61
PLIN1 O60240 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692257 1.00 MEN1 (0.90) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL692605 0.98 MEN1 (0.87) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL28112899 0.98 MEN1 (0.87) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL692500 0.98 MEN1 (0.87) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL692499 0.98 MEN1 (0.87) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL16599447 0.92 KMT2A (0.89) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL4456981 0.92 KMT2A (0.89) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL16599448 0.92 KMT2A (0.89) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL16333072 0.87 KMT2A (0.81) MEN1KMT2ARAB9APOLBSMN1; SMN2
SCHEMBL16333074 0.87 KMT2A (0.81) MEN1KMT2ARAB9APOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116794202-A Screening and application of metabolic markers of rifampicin drug-resistant tuberculosis 首都医科大学附属北京胸科医院 2023-09-22 CN claimed
EP-2710892-B1 Use of sarmentine and its analogs for controlling weeds MARRONE BIO INNOVATIONS INC (US) 2016-12-14 EP claimed
US-9179675-B2 Use of sarmentine and its analogs for controlling plant pests MARRONE BIO INNOVATIONS, INC. (US) 2015-11-10 US claimed
US-20150111749-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS PRO FARM GROUP, INC. 2015-04-23 US claimed
CN-104274831-A Composition based on naturally derived peptide and inflammation inhibitor and/or anti-oxidation compound SOO TUCK POOI 2015-01-14 CN claimed
EP-2710892-A2 Use of sarmentine and its analogs for controlling plant pests Marrone Bio Innovations, Inc. (US) 2014-03-26 EP claimed
US-20130281294-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS PRO FARM GROUP, INC. 2013-10-24 US claimed
US-20130196013-A1 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS MARRONE BIO INNOVATIONS, INC. (US) 2013-08-01 US claimed
EP-2601840-A2 Chemical and biological agents for the control of molluscs Marrone Bio Innovations, Inc. (US) 2013-06-12 EP claimed
US-20130121978-A1 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS MARRONE BIO INNOVATIONS, INC. (US) 2013-05-16 US claimed
EP-2421375-A2 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS Marrone Bio Innovations, Inc. (US) 2012-02-29 EP claimed
US-20110021358-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS MARRONE BIO INNOVATIONS, INC. (US) 2011-01-27 US claimed
WO-2010123894-A2 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS MARRONE BIO INNOVATIONS, INC. (US) 2010-10-28 WO claimed
US-20100266717-A1 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS MARRONE BIO INNOVATIONS, INC. (US) 2010-10-21 US claimed
CN-101417969-A Cinnamoyl pyrrolidine derivates and preparation method and use thereof NANJING ZHONGRUI PHARMACEUTICA (CN) 2009-04-29 CN claimed
CN-116794202-A Screening and application of metabolic markers of rifampicin drug-resistant tuberculosis 首都医科大学附属北京胸科医院 2023-09-22 CN disclosed
US-9832996-B2 Use of sarmentine and its analogues with an herbicide, and compositions thereof MARRONE BIO INNOVATIONS, INC. (US) 2017-12-05 US disclosed
CN-101417969-A Cinnamoyl pyrrolidine derivates and preparation method and use thereof NANJING ZHONGRUI PHARMACEUTICA (CN) 2009-04-29 CN disclosed
US-4128554-A Process for the preparation of carboxylic acid amides from organic halides UNIVERSITY OF DELAWARE (US) 1978-12-05 US disclosed
US-3988358-A Process for the preparation of carboxylic acid esters from organic halides THE UNIVERSITY OF DELAWARE (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100266717-A1 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS ACHE, POLI, POLL MEN1 3759/4885KMT2A 1501/4885RAB9A 448/4885
US-20130281294-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS SARM1, SMOX, STOM MEN1 3542/4885KMT2A 1428/4885RAB9A 123/4885
US-20130196013-A1 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS ACHE, POLI, POLL MEN1 3759/4885KMT2A 1501/4885RAB9A 448/4885
US-20110021358-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS SARM1, SMOX, STOM MEN1 3542/4885KMT2A 1428/4885RAB9A 123/4885
US-20150111749-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS SARM1, SMOX, STOM MEN1 3542/4885KMT2A 1428/4885RAB9A 123/4885
US-20130121978-A1 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS ACHE, POLI, POLL MEN1 3759/4885KMT2A 1501/4885RAB9A 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.