Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602345 | 0.89 | DRD2 (0.41) | DRD2DRD4HTR2CALDH1A1KDM4E | |
| SCHEMBL3580789 | 0.88 | TSHR (0.46) | DRD2DRD4ALDH1A1KDM4EMAPT | |
| SCHEMBL3596527 | 0.86 | DRD2 (0.46) | DRD2DRD4HTR2CALDH1A1KDM4E | |
| SCHEMBL3602293 | 0.86 | DRD2 (0.44) | DRD2DRD4HTR2CALDH1A1KDM4E | |
| SCHEMBL3601998 | 0.85 | DRD2 (0.43) | DRD2DRD4ALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL3606189 | 0.85 | DRD2 (0.43) | DRD2DRD4HTR2CALDH1A1KDM4E | |
| SCHEMBL3604332 | 0.84 | DRD2 (0.42) | DRD2DRD4ALDH1A1KDM4EMAPT | |
| SCHEMBL3595288 | 0.84 | DRD2 (0.42) | DRD2DRD4HTR2CALDH1A1KDM4E | |
| SCHEMBL4457515 | 0.84 | DRD2 (0.44) | DRD2DRD4HTR2CALDH1A1KDM4E | |
| SCHEMBL3591371 | 0.81 | DRD2 (0.40) | DRD2DRD4ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |