Urea

Urea

SCHEMBL4457654

NC(N)=O.O=CN1CCNC1=O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
FAAH O00519 1/20 0.32
NAAA Q02083 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318462 0.89
SCHEMBL11733432 0.76
SCHEMBL11138682 0.74 KDM4E (0.37) ALDH1A1POLB
Urea SCHEMBL3098348 0.71 NPSR1 (0.36) NPSR1ALDH1A1TSHRPOLBFAAH
SCHEMBL29509848 0.70 CDC7 (0.33) ALDH1A1
SCHEMBL235821 0.69
SCHEMBL1435556 0.69
SCHEMBL11486438 0.68 NPSR1 (0.34) NPSR1ALDH1A1TSHRPOLBFAAH
SCHEMBL6639420 0.67
SCHEMBL294168 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009091350-A1 POLYCARBAMIDES, POLYCARBAMATES, AND POLYCARBAMIDE-FORMALDEHYDE AND POLYCARBAMATE-FORMALDEHYDE CONDENSATION RESINS MISSISSIPPI STATE UNIVERSITY (US) 2009-07-23 WO disclosed
US-20090149608-A1 Polycarbamides, polycarbamates, and polycarbamide-formaldehyde and polycarbamate-formaldehyde condensation resins MISSISSIPPI STATE UNIVERSITY 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149608-A1 Polycarbamides, polycarbamates, and polycarbamide-formaldehyde and polycarbamate-formaldehyde condensation resins SUV39H1, PFAS, SUV39H2 NPSR1 3784/4885ALDH1A1 2009/4885TSHR 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.