Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303847 | 0.96 | ELANE (0.58) | ELANEDDAH1ADRA2CALDH1A1KMT2A | |
| SCHEMBL31155591 | 0.96 | ELANE (0.58) | ELANEDDAH1ADRA2CALDH1A1KMT2A | |
| Iodide SCHEMBL2761751 | 0.94 | ELANE (0.56) | ELANEDDAH1ADRA2CALDH1A1KMT2A | |
| SCHEMBL18776132 | 0.81 | DDAH1 (0.53) | DDAH1ADRA2CALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28366757 | 0.79 | DDAH1 (0.59) | DDAH1ADRA2CALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4188069 | 0.79 | DDAH1 (0.59) | DDAH1ADRA2CALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16237419 | 0.78 | DDAH1 (0.62) | DDAH1ADRA2CALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4825241 | 0.76 | DDAH1 (0.56) | DDAH1ADRA2CALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL12774716 | 0.76 | DDAH1 (0.56) | DDAH1ADRA2CALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6246856 | 0.76 | DDAH1 (0.56) | DDAH1ADRA2CALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2077846-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Life Sciences Limited (IN) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008053446-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2008-05-08 | — | — | WO | disclosed |