Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757648 | 0.89 | ESR2 (0.57) | ESR1ESR2ALDH1A1CYP3A4HSD17B1 | |
| SCHEMBL4462245 | 0.86 | ESR1 (0.54) | ESR1ESR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL20880024 | 0.85 | ESR1 (0.58) | ESR1ESR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL29616024 | 0.84 | ALOX15 (0.46) | ESR1ESR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL440099 | 0.84 | ALOX15 (0.46) | ESR1ESR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL23469778 | 0.83 | ESR1 (0.61) | ESR1ESR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1448894 | 0.83 | ESR1 (0.60) | ESR1ESR2ALDH1A1CYP3A4HSD17B1 | |
| SCHEMBL29599541 | 0.83 | ESR1 (0.60) | ESR1ESR2ALDH1A1CYP3A4HSD17B1 | |
| SCHEMBL4463362 | 0.81 | ESR1 (0.58) | ESR1ESR2ALDH1A1CYP3A4HSD17B1 | |
| SCHEMBL4460177 | 0.79 | ESR1 (0.55) | ESR1ESR2ALDH1A1CYP3A4HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582355-B2 | Optical unit using plastic lenses | FUJIFILM CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-6028161-A | EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER | MITSUI CHEMICALS, INC. (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0926180-A2 | A polycarbonate copolymer and applications thereof | Mitsui Chemicals, Inc. (JP) | 1999-06-30 | — | — | EP | disclosed |