Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886802 | 1.00 | MAPT (0.67) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL13611583 | 0.87 | ALDH1A1 (0.71) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4453471 | 0.87 | ALDH1A1 (0.71) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4324521 | 0.85 | MAPT (0.81) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4324519 | 0.85 | MAPT (0.81) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13886804 | 0.83 | MAPT (0.58) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL13611637 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4459314 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL13611615 | 0.80 | MAPT (0.72) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4462860 | 0.80 | MAPT (0.72) | MAPTMEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |