Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638160 | 0.82 | USP2 (0.41) | CYP3A4MAPK1CYP2A6AHRTSHR | |
| SCHEMBL20918502 | 0.82 | USP2 (0.41) | CYP3A4MAPK1CYP2A6AHRTSHR | |
| SCHEMBL8755324 | 0.81 | TNF (0.38) | CYP3A4MAPK1CYP2A6TSHRCYP1A2 | |
| SCHEMBL1756509 | 0.81 | CYP3A4 (0.38) | CYP3A4MAPK1CYP2A6AHRTSHR | |
| SCHEMBL5411553 | 0.77 | CYP3A4 (0.59) | CYP3A4MAPK1TSHRHPGDTDP1 | |
| SCHEMBL2013956 | 0.77 | CYP3A4 (0.35) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL159338 | 0.77 | TSHR (0.39) | CYP3A4MAPK1TSHRHPGDTDP1 | |
| SCHEMBL7624160 | 0.77 | ALDH1A1 (0.37) | CYP3A4MAPK1HTR2AHTR2CHTR2B | |
| SCHEMBL3342311 | 0.77 | HTR2A (0.44) | CYP3A4MAPK1CYP2A6AHRHTR2A | |
| SCHEMBL911858 | 0.77 | CYP3A4 (0.59) | CYP3A4MAPK1TSHRHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595426-B2 | Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20080214878-A1 | Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214878-A1 | Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives | FLNB, AFF1, AFF2 | CYP3A4 109/4885MAPK1 2531/4885CYP2A6 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.