Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458242 | 1.00 | ACE (0.54) | ACEPPARGPPARAGAAKMT2A | |
| SCHEMBL4566374 | 0.83 | ACE (0.70) | ACEPPARGPPARAGAA | |
| SCHEMBL4566373 | 0.83 | ACE (0.70) | ACEPPARGPPARAGAA | |
| SCHEMBL4459598 | 0.82 | ACE (0.56) | ACEPPARGPPARAGAAACACB | |
| SCHEMBL22773802 | 0.75 | ACE (0.60) | ACEPPARGPPARAGAAMMP2 | |
| SCHEMBL22773795 | 0.75 | ACE (0.60) | ACEPPARGPPARAGAAMMP2 | |
| SCHEMBL22773803 | 0.75 | ACE (0.60) | ACEPPARGPPARAGAAMMP2 | |
| SCHEMBL22773796 | 0.75 | ACE (0.60) | ACEPPARGPPARAGAAMMP2 | |
| SCHEMBL1632958 | 0.72 | ACE (0.66) | ACEPPARGPPARAGAA | |
| SCHEMBL1634040 | 0.72 | ACE (0.56) | ACEPPARGPPARAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |