Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566373 | 0.88 | ACE (0.70) | ACEPPARGPPARAGAA | |
| SCHEMBL4566374 | 0.88 | ACE (0.70) | ACEPPARGPPARAGAA | |
| SCHEMBL9302390 | 0.84 | ACE (0.51) | ACEPPARGPPARAEPHX1GAA | |
| SCHEMBL4458242 | 0.82 | ACE (0.54) | ACEPPARGPPARAGAAACACB | |
| SCHEMBL4458236 | 0.82 | ACE (0.54) | ACEPPARGPPARAGAAACACB | |
| SCHEMBL9299211 | 0.81 | PPARA (0.62) | ACEPPARGPPARAEPHX1 | |
| SCHEMBL9299216 | 0.81 | PPARA (0.62) | ACEPPARGPPARAEPHX1 | |
| SCHEMBL9848804 | 0.79 | EPHX1 (0.53) | ACEPPARGPPARAEPHX1GAA | |
| SCHEMBL9848809 | 0.79 | EPHX1 (0.53) | ACEPPARGPPARAEPHX1GAA | |
| SCHEMBL1634040 | 0.77 | ACE (0.56) | ACEPPARGPPARAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |