Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280271 | 0.86 | MAOB (0.58) | MAOBSMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL3962253 | 0.86 | MAOB (0.61) | MAOBSMN1; SMN2NR4A2NR4A1NR4A3 | |
| SCHEMBL384341 | 0.85 | MAOB (0.78) | MAOBSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL29369517 | 0.85 | MAOB (0.78) | MAOBSMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL31336015 | 0.84 | MAOB (0.58) | MAOBSMN1; SMN2TDP1L3MBTL1NR4A2 | |
| SCHEMBL4943007 | 0.84 | MAOB (0.58) | MAOBSMN1; SMN2TDP1L3MBTL1NR4A2 | |
| SCHEMBL22438915 | 0.83 | MEN1 (0.65) | MAOBL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28256912 | 0.83 | MAOB (0.65) | MAOBSMN1; SMN2MAPTNR4A2NR4A1 | |
| SCHEMBL16016781 | 0.82 | MAOB (0.63) | MAOBSMN1; SMN2CYP2C19NR4A2NR4A1 | |
| SCHEMBL4756552 | 0.82 | MAOB (0.63) | MAOBSMN1; SMN2CYP2C9CYP2C19NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2073804-A2 | HYDROXY-SUBSTITUTED BENZOIC ACID AMIDE COMPOUNDS FOR USE IN THERAPY | Astex Therapeutics Limited (GB) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008044054-A2 | HYDROXY-SUBSTITUTED BENZOIC ACID AMIDE COMPOUNDS FOR USE IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |