Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405317 | 0.90 | SLC6A4 (0.59) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| Methyl Alcohol SCHEMBL10694365 | 0.88 | SLC6A4 (0.58) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL11143955 | 0.83 | ESR2 (0.48) | SLC6A4DRD2ESR2SLC6A2SLC6A3 | |
| SCHEMBL11143952 | 0.83 | ESR2 (0.48) | SLC6A4DRD2ESR2SLC6A2SLC6A3 | |
| SCHEMBL5400233 | 0.82 | SLC6A4 (0.56) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4648603 | 0.82 | SLC6A4 (0.56) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL11144013 | 0.81 | ESR2 (0.47) | SLC6A4DRD2ESR2SLC6A2SLC6A3 | |
| SCHEMBL11144014 | 0.81 | ESR2 (0.47) | SLC6A4DRD2ESR2SLC6A2SLC6A3 | |
| SCHEMBL28706053 | 0.81 | SLC6A4 (0.51) | SLC6A4DRD2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL14228789 | 0.80 | ESR2 (0.46) | SLC6A4DRD2ESR2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145357-A1 | IN 1-POSITION DURCH EINEN RING SUBSTITUIERTE BENZO [1, 4] DIAZEPINE ZUR VERWENDUNGS ALS ANTIDEPRESSIVA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |