Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.45 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | EYA2 | O00167 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15511901 | 0.87 | TTR (0.54) | TTRCYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL28634126 | 0.87 | TTR (0.59) | TTRCYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL24040822 | 0.85 | TTR (0.52) | TTRTDP1SLC22A12ALDH1A1LMNA | |
| SCHEMBL24419776 | 0.83 | ALDH1A1 (0.61) | TTRCYP2C19ALDH1A1ABCC4NR1I2 | |
| SCHEMBL28885871 | 0.81 | TTR (0.65) | TTRCYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL1114408 | 0.81 | TTR (1.00) | TTRCYP3A4TSHRTDP1ESR1 | |
| SCHEMBL1191399 | 0.79 | TTR (0.62) | TTRCYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL11806725 | 0.79 | TTR (0.62) | TTRCYP3A4TSHRTDP1CYP2C19 | |
| SCHEMBL4351080 | 0.79 | TTR (0.62) | TTRCYP3A4TSHRTDP1ESR1 | |
| SCHEMBL29175300 | 0.79 | TTR (0.62) | TTRCYP3A4TSHRTDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432229-B | One kind is used for the compound for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-106432229-A | Compounds for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-4918155-A | REACTING AN OLIGOMERIC POLYCARBONATE WITH A HALOGENATED BISPHENOL A AND MOLECULAR WEIGHT MODIFIER | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1990-04-17 | — | — | US | claimed |
| CN-113214624-B | Thermoplastic polycarbonate compositions with improved hydrolytic stability and tracking resistance and shaped articles thereof | 高新特殊工程塑料全球技术有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-110621741-B | Polycarbonate compositions, methods of manufacture, and methods of use | 高新特殊工程塑料全球技术有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-113214624-A | Thermoplastic polycarbonate compositions with improved hydrolytic stability and tracking resistance and shaped articles thereof | 高新特殊工程塑料全球技术有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-110621741-A | Polycarbonate compositions, methods of manufacture, and methods of use | 沙特基础工业全球技术有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-106432229-B | One kind is used for the compound for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106432229-A | Compounds for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-101379111-B | Polymerizable unsaturated compound and method for producing the same | WAKO PURE CHEM IND LTD | 2012-01-11 | — | — | CN | disclosed |
| EP-1517159-B1 | Brominated polycarbonate films | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-03-25 | — | — | EP | disclosed |
| US-4211687-A | AROMATIC POLYESTER, POLYPHENYLENE SULFIDE, HALO DIELS-ADER ADDUCT | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-07-08 | — | — | US | disclosed |
| US-4197309-A | AND THEIR OXIMES, USED TO INDUCE URICOSIC EFFECT WITHOUT DIURESIS | ALBERT ROLAND S.A. (FR) | 1980-04-08 | — | — | US | disclosed |
| US-4187259-A | Polymer blends with improved hydrolytic stability comprising a linear aromatic polyester and a methacrylate cross-linked acrylate copolymer | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-02-05 | — | — | US | disclosed |
| EP-0007171-A1 | Polymer compositions, molded articles and films with improved hydrolytic stability | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4137278-A | TRANSESTERIFICATION CATALYST | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1979-01-30 | — | — | US | disclosed |
| US-4126602-A | THERMOPLASTIC, MOLDING, HYDROLYTIC STABILITY | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4079034-A | AROMATIC POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A HALOGENATED BISPHENOL | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4051106-A | High molecular weight copolyester resins having a high degree of alternating structure | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-4051107-A | Microstructured high molecular weight-low viscosity polyester polymers | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |