Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482856 | 0.85 | PPARA (0.51) | PPARAPPARGACACBHTTALDH1A1 | |
| SCHEMBL4451939 | 0.84 | PPARA (0.44) | PPARAPPARGACACBCES2CES1 | |
| SCHEMBL31264426 | 0.82 | EPHX2 (0.51) | F2PLGPRSS1PRSS2C1S | |
| SCHEMBL5320394 | 0.81 | POLB (0.58) | PPARAPPARGACACBCYP1A2CYP3A4 | |
| SCHEMBL11218545 | 0.80 | CA2 (0.52) | PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11218542 | 0.80 | PPARA (0.46) | PPARAPPARGACACBCTBP2CYP1A2 | |
| SCHEMBL5791802 | 0.79 | CTBP2 (0.64) | F2PLGPRSS1PRSS2C1S | |
| SCHEMBL7502088 | 0.79 | CYP4F2 (0.56) | PPARAPPARGACACBCYP3A4CYP2C19 | |
| SCHEMBL9784096 | 0.79 | ACACB (0.46) | PPARAPPARGACACBCYP3A4CYP2C19 | |
| SCHEMBL19619634 | 0.79 | NPC1 (0.50) | PPARAPPARGACACBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | claimed |
| EP-1801224-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUENT-OXY-3-(4-SUBSTITUENT-OXYPHENYL)PROPIONIC ACID DERIVATIVE | Kaneka Corporation (JP) | 2007-06-27 | — | — | EP | claimed |
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1801224-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUENT-OXY-3-(4-SUBSTITUENT-OXYPHENYL)PROPIONIC ACID DERIVATIVE | Kaneka Corporation (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801224-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUENT-OXY-3-(4-SUBSTITUENT-OXYPHENYL)PROPIONIC ACID DERIVATIVE | Kaneka Corporation (JP) | 2007-06-27 | — | — | EP | disclosed |