SCHEMBL4458922

SCHEMBL4458922

Oc1ccc(C(c2ccc(O)c(Cl)c2)c2ccc(O)c(Cl)c2)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.54
TSHR P16473 3/20 0.54
ESR2 Q92731 3/20 0.50
CA2 P00918 2/20 0.50
CA1 P00915 1/20 0.50
ESR1 P03372 2/20 0.45
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CYP2C19 P33261 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CYP19A1 P11511 1/20 0.39
CYP3A4 P08684 3/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29465800 1.00 HSD17B10 (0.54) HSD17B10TSHRESR2CA2CA1
SCHEMBL1596153 0.98 HSD17B10 (0.52) HSD17B10TSHRESR2CA2CA1
SCHEMBL1758433 0.91 ESR2 (0.48) HSD17B10TSHRESR2CA2CA1
SCHEMBL1758423 0.91 ESR2 (0.48) HSD17B10TSHRESR2CA2CA1
SCHEMBL1596005 0.85 HSD17B10 (0.54) HSD17B10TSHRESR2CA2CA1
SCHEMBL30343463 0.85 HSD17B10 (0.54) HSD17B10TSHRESR2CA2CA1
SCHEMBL1758242 0.85 ESR2 (0.52) HSD17B10TSHRESR2CA2CA1
SCHEMBL19301757 0.83 HSD17B10 (0.52) HSD17B10TSHRESR2CA2CA1
SCHEMBL502532 0.81 HSD17B10 (0.50) HSD17B10TSHRESR2CA2CA1
SCHEMBL31716485 0.81 HSD17B10 (0.50) HSD17B10TSHRESR2CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646613-B1 A branched polycarbonate and a process for producing the same IDEMITSU PETROCHEMICAL CO (JP) 2002-02-27 EP claimed
EP-0496258-B1 Polymer composition containing a branched polycarbonate IDEMITSU PETROCHEMICAL CO (JP) 2001-06-20 EP claimed
US-5625027-A Branched polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-04-29 US claimed
US-5473046-A Interfacial polymerization; heat resistance, corrosion resistance IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-12-05 US claimed
EP-0646613-A2 A branched polycarbonate and a process for producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1995-04-05 EP claimed
US-5243018-A Melt properties suitable for blow molding; appliances, business automation equipment, construction materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-09-07 US claimed
EP-0496258-A2 Polymer composition containing a branched polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
US-12398266-B2 Polycarbonate resin composition IDEMITSU KOSAN CO., LTD. (JP) 2025-08-26 US disclosed
US-12371564-B2 Resin composition and method of producing resin composition, and method of producing resin molding SONY CORPORATION (JP) 2025-07-29 US disclosed
US-12297349-B2 Transparent resin composition and transparent resin molded article Sony Group Corporation (JP) 2025-05-13 US disclosed
US-12024629-B2 Polycarbonate-based resin, production method therefor, and polycarbonate-based resin composition IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-20240199849-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES IDEMITSU KOSAN CO.,LTD. (JP) 2024-06-20 US disclosed
US-20240150574-A1 POLYCARBONATE RESIN COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
US-5314949-A Branched IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-05-24 US disclosed
US-5283314-A Polymerizing an oligomer of a dihydric phenol and a branching agent with a dihydric alcohol and a monohydric phenol with stirring IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-02-01 US disclosed
US-5243018-A Melt properties suitable for blow molding; appliances, business automation equipment, construction materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-09-07 US disclosed
EP-0496257-A2 Polymer composition comprising a branched polycarbonate and a polyester IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-07-29 EP disclosed
EP-0496258-A2 Polymer composition containing a branched polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-07-29 EP disclosed
US-5104964-A Blow molding IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-04-14 US disclosed
EP-0411433-A2 Branched polycarbonate and process for production thereof IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-02-06 EP disclosed