SCHEMBL502532

SCHEMBL502532

CC(c1ccc(O)c(Cl)c1)c1ccc(O)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.50
TSHR P16473 2/20 0.50
ESR2 Q92731 4/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
ESR1 P03372 3/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
TYR P14679 1/20 0.43
HIF1A Q16665 3/20 0.42
ALOX12 P18054 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
CYP2D6 P10635 1/20 0.40
RECQL P46063 4/20 0.39
TDP1 Q9NUW8 4/20 0.39
KDM4E B2RXH2 3/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31716485 1.00 HSD17B10 (0.50) HSD17B10TSHRESR2CA1CA2
SCHEMBL28384061 0.90 ESR2 (0.53) HSD17B10TSHRESR2CA1CA2
SCHEMBL105261 0.86 ALDH1A1 (0.57) HSD17B10TSHRESR2CA1CA2
SCHEMBL11789449 0.84 TSHR (0.48) HSD17B10TSHRESR2CA1CA2
SCHEMBL11357081 0.83 HSD17B10 (0.46) HSD17B10TSHRESR2CA1CA2
SCHEMBL20666764 0.83 HSD17B10 (0.46) HSD17B10TSHRESR2CA1CA2
SCHEMBL1596005 0.81 HSD17B10 (0.54) HSD17B10TSHRESR2CA1CA2
SCHEMBL29465800 0.81 HSD17B10 (0.54) HSD17B10TSHRESR2CA1CA2
SCHEMBL4458922 0.81 HSD17B10 (0.54) HSD17B10TSHRESR2CA1CA2
SCHEMBL30343463 0.81 HSD17B10 (0.54) HSD17B10TSHRESR2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671167-B2 Poly(arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-02 US claimed
US-20090247724-A1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-01 US claimed
EP-1969030-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2008-09-17 EP claimed
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP claimed
WO-2007067669-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO claimed
US-20070135609-A1 Poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-06-14 US claimed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
US-5969079-A HEAT RESISTANT, HIGH STRENGTH AEROSPACE ENGINEERING THERMOPLASTICS THE BOEING COMPANY (US) 1999-10-19 US claimed
EP-3636692-B1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECH BV (NL) 2026-04-29 EP disclosed
US-12503593-B2 Curable thermosetting composition including poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-12-23 US disclosed
EP-3919545-B1 CURABLE THERMOSETTING COMPOSITION INCLUDING POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECH BV (NL) 2025-10-22 EP disclosed
US-20240376240-A1 PHENYLENE ETHER OLIGOMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE PHENYLENE ETHER OLIGOMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-11-14 US disclosed
US-20240174790-A1 CAPPED BISPHENOL POLYINDANE OLIGOMER AND COMPOSITION, METHOD OF MANUFACTURE, AND ARTICLES MADE THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-05-30 US disclosed
US-4322521-A Process for producing halogenated aromatic polyesters CELANESE CORPORATION (US) 1982-03-30 US disclosed
EP-0007940-A1 SOLUTION POLYMERIZED HALOGENATED POLYESTERS CELANESE CORPORATION (US) 1980-02-20 EP disclosed
US-4150068-A OLIGOMERIC POLYHALOPHOSPHATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-04-17 US disclosed
WO-1979000071-A1 SOLUTION POLYMERIZED HALOGENATED POLYESTERS CELANESE CORP (US) 1979-02-22 WO disclosed
US-4132705-A Process for preparing a halogenated aromatic polyester having a predetermined molecular weight by solution polymerization technique CELANESE CORPORATION (US) 1979-01-02 US disclosed
US-4066623-A INVERSE INTERFACIAL POLYMERIZATION FOR PREPARING CERTAIN HALOGENATED AROMATIC POLYESTERS CELANESE CORPORATION (US) 1978-01-03 US disclosed