Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769203 | 0.89 | ACHE (0.63) | ACHETSHR | |
| SCHEMBL13055388 | 0.87 | MAPT (0.42) | ACHETSHRMEN1KMT2AMAPT | |
| SCHEMBL29940 | 0.87 | ACHE (0.56) | ACHETSHR | |
| SCHEMBL14328774 | 0.85 | EPHX1 (0.59) | ACHETSHR | |
| SCHEMBL8769159 | 0.85 | EPHX1 (0.59) | ACHETSHR | |
| SCHEMBL8769636 | 0.85 | EPHX1 (0.59) | ACHETSHR | |
| SCHEMBL6332791 | 0.85 | EPHX1 (0.59) | ACHETSHR | |
| SCHEMBL6332081 | 0.85 | EPHX1 (0.59) | ACHETSHR | |
| SCHEMBL8769221 | 0.85 | EPHX1 (0.59) | ACHETSHR | |
| SCHEMBL10349440 | 0.85 | EPHX1 (0.59) | ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101065157-A | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-31 | — | — | CN | claimed |
| CN-111936487-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-112312909-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113710660-B | DOT1L degradation agent and application thereof | 达纳-法伯癌症研究公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117820226-A | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117751114-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117624045-A | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117603138-A | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-113896685-B | Indoleamine-2, 3-dioxygenase (IDO) inhibitors | 益方生物科技(上海)股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-101065407-A | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-31 | — | — | CN | disclosed |
| CN-101065157-A | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-31 | — | — | CN | disclosed |
| CN-101065686-A | Wettable hydrogels containing reactive hydrophilic polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-31 | — | — | CN | disclosed |
| EP-1601723-A4 | DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHSON & JOHNSON VISION CARE I (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2007047716-A2 | SURFACE-MODIFIED MEDICAL DEVICES AND METHOD OF MAKING | BAUSCH & LOMB INCORPORATED (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20070087113-A1 | Surface-modified medical devices and method of making | BAUSCH & LOMB INCORPORATED | 2007-04-19 | — | — | US | disclosed |
| EP-1601723-A2 | DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | J & J Vision Care, Inc. (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004081105-A2 | DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JONHSON AND JOHNSON VISION CARE, INC. (US) | 2004-09-23 | — | — | WO | disclosed |
| US-4260552-A | INSECTICIDES, HERBICIDES | UNIROYAL, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4160846-A | Method for controlling insects with tetrasubstituted organotin compounds | UNIROYAL, INC. (US) | 1979-07-10 | — | — | US | disclosed |