Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 9/20 | 0.56 |
| ▸ | DRD5 | P21918 | 8/20 | 0.56 |
| ▸ | DRD2 | P14416 | 8/20 | 0.56 |
| ▸ | DRD3 | P35462 | 8/20 | 0.56 |
| ▸ | DRD4 | P21917 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843474 | 0.82 | DRD1 (0.79) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL4317508 | 0.82 | DRD1 (0.79) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL13068804 | 0.79 | DRD1 (0.56) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11823744 | 0.79 | DRD1 (0.85) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11819711 | 0.79 | DRD1 (0.85) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL3698679 | 0.78 | DRD1 (0.86) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL14340583 | 0.77 | DRD1 (0.88) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29515933 | 0.77 | DRD1 (0.88) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL4320078 | 0.77 | HRH3 (0.59) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL13033081 | 0.77 | DRD1 (0.54) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |