SCHEMBL4459353

SCHEMBL4459353

CCCCCC(Br)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.44
HTR2A P28223 1/20 0.42
CSNK1E P49674 1/20 0.41
OPRM1 P35372 2/20 0.41
OPRD1 P41143 2/20 0.41
OPRK1 P41145 2/20 0.41
OPRL1 P41146 2/20 0.41
CYP19A1 P11511 3/20 0.41
NAAA Q02083 2/20 0.40
POLB P06746 2/20 0.40
CNR2 P34972 1/20 0.40
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27692872 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL27806681 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL11806604 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL6681848 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL6685358 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL8728015 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL14636124 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL7573099 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL22734895 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL2404354 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447459-A Method for synthesizing rotigorskite key intermediate by using chiral phase transfer catalyst as catalyst 瑞博(杭州)医药科技有限公司 2024-01-26 CN claimed
CN-112960656-A Preparation method of vanadium nitride nanoparticle composite material for lithium-sulfur battery 福建师范大学 2021-06-15 CN claimed
CN-109232520-A 5,5 '-two (styryl) -3,3 '-union II thiophene derivants, synthetic method and its application 上海应用技术大学 2019-01-18 CN claimed
CN-109232519-A 4,4 '-two (styryl) -3,3 '-union II thiophene derivants, synthetic method and its application 上海应用技术大学 2019-01-18 CN claimed
CN-106749318-B A kind of organic field effect tube material and its synthetic method and application based on oxa- condensed ring class 苏州大学 2019-01-08 CN claimed
CN-106349287-B Quaternary phosphonium salt class compound with piezallochromy property and its preparation method and application 四川大学 2018-12-21 CN claimed
CN-105820151-B 2,2 '-di (styryl) -3, 3' -bithiophene derivative, synthetic method and application thereof 上海应用技术学院 2018-05-01 CN claimed
CN-106397100-A Synthesis method of amorolfine drug intermediate p-tertiary amyl benzyl bromide 厦门市凯尔利信息科技有限公司 2017-02-15 CN claimed
CN-106349287-A Quaternary phosphonium salts compound with piezochromism property and preparation method and application of quaternary phosphonium salts compound 四川大学 2017-01-25 CN claimed
CN-105820151-A 2,2 '-di (styryl) -3, 3' -bithiophene derivative, synthetic method and application thereof 上海应用技术学院 2016-08-03 CN claimed
US-12607789-B2 Display panel and method of manufacturing the same and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-21 US disclosed
US-20250311610-A1 COPOLYMER, AND COMPOSITION, LIQUID COMPOSITION, AND ELECTROLUMINSECNT DEVICE INCLUDING THE COPOLYMER SAMSUNG DISPLAY CO., LTD. (KR) 2025-10-02 US disclosed
EP-4624510-A1 COPOLYMER, COMPOSITION, LIQUID COMPOSITION, AND ELECTROLUMINSECNT DEVICE INCLUDING THE COPOLYMER Samsung Electronics Co., Ltd. (KR) 2025-10-01 EP disclosed
CN-115850002-B Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2025-05-23 CN disclosed
CN-118076663-A Composition and ink composition 住友化学株式会社 2024-05-24 CN disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
EP-0905172-A1 POLYSILANES AND POSITIVE HOLE TRANSPORTING MATERIALS OSAKA GAS CO., LTD. (JP) 1999-03-31 EP disclosed
WO-1997010247-A1 CLAVULANIC ACID DERIVATIVES FOR TREATING ATHEROSCLEROSIS SMITHKLINE BEECHAM P.L.C. (GB) 1997-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12607789-B2 Display panel and method of manufacturing the same and electronic device CD63, CD2, NECTIN4 SIGMAR1 2867/4885HTR2A 1356/4885CSNK1E 1880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.