SCHEMBL4459381

SCHEMBL4459381

CCc1[c]ccc(F)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27694451 0.79 TAAR1 (0.31)
SCHEMBL455831 0.78
SCHEMBL4998228 0.78
SCHEMBL15063705 0.77 HTR1A (0.33)
SCHEMBL2139795 0.77
SCHEMBL6826576 0.72
SCHEMBL2344895 0.71
SCHEMBL5326137 0.71 TAAR1 (0.31)
SCHEMBL148941 0.70
SCHEMBL224656 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007135529-A2 AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS PFIZER PRODUCTS INC. (US) 2007-11-29 WO claimed
WO-2007135527-A2 BENZIMIDAZOLYL COMPOUNDS PFIZER PRODUCTS INC. (US) 2007-11-29 WO claimed
US-7605111-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-20 US disclosed
US-7459414-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2008-12-02 US disclosed
WO-2007135527-A2 BENZIMIDAZOLYL COMPOUNDS PFIZER PRODUCTS INC. (US) 2007-11-29 WO disclosed
WO-2007135529-A2 AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS PFIZER PRODUCTS INC. (US) 2007-11-29 WO disclosed
US-20050187110-A1 mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants MAETZKE THOMAS (CH) 2005-08-25 US disclosed
US-20050164883-A1 agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides MAETZKE THOMAS (CH) 2005-07-28 US disclosed
US-6894005-B1 Heterocyclic compound containing phenyl groups; postemergence herbicides SYNGENTA CROP PROTECTION, INC. (US) 2005-05-17 US disclosed