Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444854 | 0.78 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL6755694 | 0.75 | MMP1 (0.43) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL18312607 | 0.71 | MEN1 (0.43) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL10510602 | 0.71 | MEN1 (0.43) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL15354729 | 0.70 | MEN1 (0.37) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL15354753 | 0.70 | MEN1 (0.37) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL13674448 | 0.69 | MEN1 (0.39) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL14613751 | 0.68 | MMP1 (0.36) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL1831392 | 0.68 | MMP1 (0.36) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL18312771 | 0.68 | MMP1 (0.36) | MMP1MMP2MMP8MMP13MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029153-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | Phenomix Corporation (US) | 2009-03-04 | — | — | EP | claimed |
| WO-2007089618-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2007-08-09 | — | — | WO | claimed |