Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
| ▸ | PPARA | Q07869 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459836 | 1.00 | PPARG (0.51) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL3739737 | 0.84 | LDHA (0.51) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL7676911 | 0.84 | LDHA (0.51) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL4460123 | 0.80 | PPARA (0.56) | PPARGPPARAMEN1CYP1A2CYP3A4 | |
| SCHEMBL13809480 | 0.78 | BLM (0.65) | MEN1CYP1A2CYP3A4MAPTKMT2A | |
| SCHEMBL2164933 | 0.78 | PPARG (0.58) | PPARGPPARAMEN1CYP1A2MAPT | |
| SCHEMBL2164934 | 0.78 | PPARG (0.58) | PPARGPPARAMEN1CYP1A2MAPT | |
| SCHEMBL1275761 | 0.77 | SMN1; SMN2 (0.55) | PPARGPPARACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3361395 | 0.77 | SMN1; SMN2 (0.55) | PPARGPPARACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL180161 | 0.77 | SMN1; SMN2 (0.55) | PPARGPPARACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |