Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138558 | 0.84 | MAPT (0.57) | MAPTCRHBPCRHR2L3MBTL1DRD2 | |
| SCHEMBL8482260 | 0.83 | ALDH1A1 (0.57) | MAPTALDH1A1GAA | |
| SCHEMBL14515208 | 0.83 | GAA (0.53) | MAPTCRHBPCRHR2L3MBTL1DRD2 | |
| SCHEMBL5044155 | 0.83 | GAA (0.53) | MAPTCRHBPCRHR2L3MBTL1DRD2 | |
| SCHEMBL14515221 | 0.83 | GAA (0.53) | MAPTCRHBPCRHR2L3MBTL1DRD2 | |
| SCHEMBL11664062 | 0.81 | MAPT (0.51) | MAPTCRHBPCRHR2L3MBTL1DRD2 | |
| SCHEMBL6228523 | 0.80 | MAPT (0.65) | MAPTL3MBTL1DRD2DRD4DRD3 | |
| SCHEMBL9482339 | 0.80 | MAPT (0.50) | MAPTCRHBPCRHR2L3MBTL1DRD2 | |
| SCHEMBL9482342 | 0.80 | MAPT (0.50) | MAPTCRHBPCRHR2L3MBTL1DRD2 | |
| SCHEMBL2564281 | 0.80 | TDP1 (0.56) | MAPTCRHBPCRHR2L3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595181-B2 | From thermophilic microorganisms; active at high temperature | PROTEUS S.A. (FR) | 2009-09-29 | — | — | US | disclosed |
| EP-1727909-A1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | Goldschmidt GmbH (DE) | 2006-12-06 | — | — | EP | disclosed |
| EP-1668124-A2 | THERMOSTABLE HYDROLASE | Goldschmidt GmbH (DE) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005093089-A1 | METHOD AND TEST-KIT FOR THE DETECTION AND QUANTIFICATION OF ORGANISMS | GOLDSCHMIDT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG (DE) | 2005-10-06 | — | — | WO | disclosed |
| US-20050112644-A1 | Thermostable hydrolase | EVONIK GOLDSCHMIDT GMBH (DE) | 2005-05-26 | — | — | US | disclosed |
| WO-2005040370-A2 | THERMOSTABLE HYDROLASE | GOLDSCHMIDT GMBH (DE) | 2005-05-06 | — | — | WO | disclosed |