Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CDC42 | P60953 | 1/20 | 0.39 |
| ▸ | RAC1 | P63000 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455244 | 0.83 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL4459829 | 0.81 | ACACB (0.47) | ACACBAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL28776058 | 0.73 | ACACB (0.51) | ACACBAKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL31037707 | 0.71 | FFAR1 (0.51) | ACACBTSHRPPARAKMT2APPARG | |
| SCHEMBL7814760 | 0.71 | FFAR1 (0.51) | ACACBTSHRPPARAKMT2APPARG | |
| SCHEMBL5322553 | 0.71 | PPARA (0.57) | CYP1A2TSHRPPARACYP2D6CYP2C19 | |
| SCHEMBL4451912 | 0.71 | ESR1 (0.43) | ACACBAKR1C3AKR1C2PTGS1CYP1A2 | |
| SCHEMBL6055221 | 0.70 | ACACB (0.47) | ACACBCYP1A2PPARACYP2D6CYP2C19 | |
| SCHEMBL8036077 | 0.70 | ACACB (0.47) | ACACBCYP1A2TSHRPPARACYP2D6 | |
| SCHEMBL9008858 | 0.70 | ACACB (0.41) | ACACBTSHRNPSR1ELANESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |