Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CDC42 | P60953 | 1/20 | 0.37 |
| ▸ | RAC1 | P63000 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460120 | 0.81 | ACACB (0.45) | ACACBPPARACYP1A2MEN1CYP3A4 | |
| SCHEMBL6055221 | 0.76 | ACACB (0.47) | ACACBPPARACYP1A2MEN1CYP3A4 | |
| SCHEMBL28776058 | 0.75 | ACACB (0.51) | ACACBPPARACYP1A2MEN1CYP3A4 | |
| SCHEMBL18287905 | 0.74 | ELANE (0.55) | ACACBPPARACYP1A2MEN1CYP3A4 | |
| SCHEMBL7525226 | 0.74 | LMNA (0.54) | CYP2D6PTGS2LMNAHPGDMAPK1 | |
| SCHEMBL10024370 | 0.74 | LMNA (0.54) | CYP2D6PTGS2LMNAHPGDMAPK1 | |
| SCHEMBL180160 | 0.74 | LMNA (0.54) | CYP2D6PTGS2LMNAHPGDMAPK1 | |
| SCHEMBL5316315 | 0.74 | ACACB (0.50) | ACACBPPARACYP1A2MEN1CYP3A4 | |
| SCHEMBL14465787 | 0.74 | ACACB (0.50) | ACACBPPARACYP1A2MEN1CYP3A4 | |
| SCHEMBL24360844 | 0.73 | GABBR2 (0.44) | ACACBPPARACYP1A2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |