SCHEMBL4460185

SCHEMBL4460185

O=C(OCC1CO1)C1C=CC(C(=O)OCC2CO2)CC1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.40
MGLL Q99685 4/20 0.40
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270992 0.89 TP53 (0.49) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL27329585 0.83 TP53 (0.54) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL10036675 0.81 TP53 (0.56) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL15095483 0.80 TP53 (0.58) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL7656832 0.78 TP53 (0.66) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL7860984 0.78 TP53 (0.66) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL31688117 0.78 TP53 (0.85) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL285188 0.78 TP53 (0.66) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL9347713 0.78 TP53 (0.66) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL1045748 0.75 TP53 (0.74) TP53CYP3A4ALDH1A1LMNAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
EP-0678533-B1 Process and composition for preparing a dental polymer product DENTSPLY GMBH (DE) 2004-09-01 EP disclosed