SCHEMBL4460407

SCHEMBL4460407

CC(O)CC(CC(=O)O)N1CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.36
KDM4E B2RXH2 3/20 0.35
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TP53 P04637 1/20 0.33
REN P00797 1/20 0.33
ACE P12821 1/20 0.33
MAPT P10636 1/20 0.32
HRH3 Q9Y5N1 2/20 0.32
GABRR1 P24046 2/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4181286 0.72 KDM4E (0.54) SLC22A6KDM4ECACNA2D1CACNB3CACNA1C
SCHEMBL1174393 0.72
SCHEMBL10885050 0.69 SLC6A3 (0.45) KDM4EALDH1A1TP53RENACE
SCHEMBL3128590 0.69 KDM4E (0.49) SLC22A6KDM4ECACNA2D1CACNB3CACNA1C
SCHEMBL10025245 0.69 SLC6A3 (0.49) KDM4EALDH1A1TP53RENACE
SCHEMBL7613286 0.69 CACNA2D1 (0.52) SLC22A6CACNA2D1CACNB3CACNA1CPGR
SCHEMBL27898435 0.69 SLC22A6 (0.46) SLC22A6CACNA2D1CACNB3CACNA1CPGR
SCHEMBL18113005 0.69 SLC22A6 (0.46) SLC22A6CACNA2D1CACNB3CACNA1CPGR
SCHEMBL976030 0.69 SLC22A6 (0.60) SLC22A6CACNA2D1CACNB3CACNA1CPGR
SCHEMBL8292735 0.69 SLC22A6 (0.60) SLC22A6CACNA2D1CACNB3CACNA1CPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5648417-A ACID AND WEAR RESISTANCE NIPPON PAINT CO., LTD. (JP) 1997-07-15 US claimed
EP-0682681-A1 COLOR COATING COMPOSITION NIPPON PAINT CO., LTD. (JP) 1995-11-22 EP claimed
WO-1995015362-A1 COLOR COATING COMPOSITION NIPPON PAINT CO., LTD. (JP) 1995-06-08 WO claimed
US-7541064-B2 Method of forming multilayer coating film including water-borne basecoat on automobile substrate NIPPON PAINT CO., LTD. (JP) 2009-06-02 US disclosed
US-7034066-B2 Water-borne base coating composition for automobiles NIPPON PAINT CO., LTD. (JP) 2006-04-25 US disclosed
US-20060079604-A1 Water-borne base coating composition for automobiles NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2006-04-13 US disclosed
US-20050025978-A1 Method of finish-coating automotive bodies and finished automotive bodies NIPPON PAINT CO., LTD. (JP) 2005-02-03 US disclosed
EP-1486263-A2 Method of finish-coating automotive bodies and finished automotive bodies Nippon Paint Co., Ltd. (JP) 2004-12-15 EP disclosed
US-20040096590-A1 Water-based coating composition and method of forming layered coating film NIPPON PAINT CO., LTD. (JP) 2004-05-20 US disclosed
US-6726961-B2 WATER-BASED BASE COAT COMPRISES A POLYETHER POLYOL OF GIVEN HYDROXYL NUMBER, AND GIVEN WATER TOLERANCE, AND A C1-C2 ALKYL (METH)ACRYLATE COPOLYMER, FOLLOWED BY A CLEAR COAT; FLIP-FLOP PROPERTIES NIPPON PAINT CO., LTD. (JP) 2004-04-27 US disclosed
EP-1384758-A1 WATER-BASED COATING COMPOSITION AND METHOD OF FORMING LAYERED COATING FILM Nippon Paint Co., Ltd. (JP) 2004-01-28 EP disclosed
US-20030175435-A1 Acrylated ester copolymer NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2003-09-18 US disclosed
US-20020009550-A1 Method of forming coating NIPPON PAINT CO., LTD. (JP) 2002-01-24 US disclosed
US-20020007769-A1 Coating composition NIPPON PAINT CO., LTD. (JP) 2002-01-24 US disclosed