SCHEMBL446069

SCHEMBL446069

[CH2]C1=NCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3742115 0.67 NISCH (0.56)
SCHEMBL11774788 0.64
SCHEMBL11626918 0.63
SCHEMBL1776390 0.63
Ethylene Thiourea SCHEMBL137081 0.62
SCHEMBL3957418 0.62
SCHEMBL315734 0.62
SCHEMBL16730 0.62
SCHEMBL11563018 0.62
SCHEMBL127079 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 581 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230416258-A1 BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF CHINA PHARMACEUTICAL UNIVERSITY (CN) 2023-12-28 US claimed
EP-4242210-A1 NEW BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF China Pharmaceutical University (CN) 2023-09-13 EP claimed
CN-116507628-A Novel benzodiazepine compound, preparation method and application thereof 中国药科大学 2023-07-28 CN claimed
EP-3312292-B1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS PROMEGA CORP (US) 2019-09-25 EP claimed
EP-3312292-A1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS Promega Corporation (US) 2018-04-25 EP claimed
US-20160244435-A1 EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS THE SCRIPPS RESEARCH INSTITUTE (US) 2016-08-25 US claimed
EP-3010345-A1 EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS The Regents of The University of California (US) 2016-04-27 EP claimed
WO-2014205414-A1 EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-12-24 WO claimed
EP-1797051-B1 BENZOXAZINE AND QUINOXALINE DERIVATIVES AND USES HOFFMANN LA ROCHE (CH) 2010-08-11 EP claimed
EP-1392660-B1 SUBSTITUTED BENZOYLCYCLOHEXENONES AND THEIR USE AS HERBICIDAL AGENTS BAYER AG (DE) 2010-08-04 EP claimed
US-5013731-A Bactericides ICI PHARMA (FR) 1991-05-07 US claimed
US-5008258-A Antibiotics I.C.I.-PHARMA (FR) 1991-04-16 US claimed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP claimed
US-4868173-A CONTAIN AMINE SALT GROUP ICI PHARMA (FR) 1989-09-19 US claimed
EP-0304155-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-02-22 EP claimed
EP-0300665-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-01-25 EP claimed
EP-0300664-A2 Cephalosporin compounds ZENECA Pharma S.A. (FR) 1989-01-25 EP claimed
EP-0225182-A2 Cephalosporin compounds ICI PHARMA (FR) 1987-06-10 EP claimed
EP-0182633-A2 Cephalosporin derivatives ICI PHARMA (FR) 1986-05-28 EP claimed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP claimed