SCHEMBL4460780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4471046	0.87	MEN1 (0.61)	CDK2CA1CA2CA9CA12
	SCHEMBL4466766	0.85	CDK2 (0.62)	CDK2CA1CA2CA9CA12
	SCHEMBL13931766	0.84	CDK2 (0.48)	CDK2CA1CA2CA9CA12
	SCHEMBL4475239	0.84	CDK2 (0.62)	CDK2CA1CA2CA9CA12
	SCHEMBL4476707	0.84	CDK2 (0.62)	CDK2CA1CA2CA9CA12
	SCHEMBL5510994	0.84	CA12 (0.50)	CDK2CA1CA2CA9CA12
	SCHEMBL13918111	0.84	IKBKB (0.54)	CDK2CA1CA2CA9CA12
	SCHEMBL13931858	0.82	CDK2 (0.46)	CDK2CA1CA2CA9CA12
	Gw831091X SCHEMBL4464647	0.78	CDK2 (0.65)	CDK2CA1CA2CA9CA12
	SCHEMBL27580667	0.77	CA2 (0.78)	CDK2CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.