Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460931 | 1.00 | CES1 (0.50) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL4453613 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1PPARGPPARD | |
| SCHEMBL4453612 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1PPARGPPARD | |
| SCHEMBL4458032 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1PPARGPPARD | |
| SCHEMBL4452638 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1PPARGPPARD | |
| SCHEMBL4458027 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1PPARGPPARD | |
| SCHEMBL4458025 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1PPARGPPARD | |
| SCHEMBL13936169 | 0.86 | — | — | |
| SCHEMBL4452114 | 0.86 | — | — | |
| SCHEMBL4452110 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048461-A1 | Regulators of Bacterial Signalling Pathways | BIOSIGNAL LIMITED (AU) | 2009-02-19 | — | — | US | disclosed |
| EP-1765755-A4 | REGULATORS OF BACTERIAL SIGNALLING PATHWAYS | BIOSIGNAL LTD (AU) | 2008-05-21 | — | — | EP | disclosed |
| EP-1765755-A1 | REGULATORS OF BACTERIAL SIGNALLING PATHWAYS | Biosignal Limited (AU) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123645-A1 | REGULATORS OF BACTERIAL SIGNALLING PATHWAYS | BIOSIGNAL LIMITED (AU) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048461-A1 | Regulators of Bacterial Signalling Pathways | MRPL21, FNTB, ATF1 | CES1 4367/4885CES2 4511/4885ALDH1A1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.