Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673792 | 0.68 | GPR119 (0.55) | GPR119MDM2 | |
| SCHEMBL27652127 | 0.65 | GPR119 (0.46) | GPR119 | |
| SCHEMBL387913 | 0.65 | GPR119 (0.48) | GPR119 | |
| SCHEMBL390764 | 0.65 | GPR119 (0.72) | GPR119KMT2AMAPT | |
| SCHEMBL1673697 | 0.64 | GPR119 (0.53) | GPR119KMT2AMAPT | |
| SCHEMBL5261880 | 0.64 | GPR119 (0.57) | GPR119KMT2AMAPT | |
| SCHEMBL387943 | 0.64 | GPR119 (0.47) | GPR119 | |
| SCHEMBL388922 | 0.63 | GPR119 (0.46) | GPR119 | |
| SCHEMBL27755050 | 0.58 | GPR119 (0.43) | GPR119 | |
| SCHEMBL2024106 | 0.57 | CYP3A4 (0.69) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808168-B1 | Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level | ARENA PHARM INC (US) | 2009-06-03 | — | — | EP | disclosed |