Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.93 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | CHKA | P35790 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948862 | 1.00 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3947402 | 1.00 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL2323473 | 1.00 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3948090 | 1.00 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3947407 | 1.00 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL733597 | 1.00 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3948084 | 1.00 | ALDH1A1 (0.93) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3949743 | 0.97 | ALDH1A1 (0.94) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3947986 | 0.97 | ALDH1A1 (0.94) | ALDH1A1CA2CHKAKMT2AMEN1 | |
| SCHEMBL3947992 | 0.97 | ALDH1A1 (0.94) | ALDH1A1CA2CHKAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 684 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715422-B | Indene derivative, preparation method and the pharmaceutical composition for being used to prevent or treat retinal disease comprising it as active constituent | 忠南大学校产学协力团 | 2019-11-19 | — | — | CN | claimed |
| CN-110291087-A | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders | 阿尔维纳斯运营股份有限公司 | 2019-09-27 | — | — | CN | claimed |
| CN-106795179-B | Kinase inhibitor | 锦州奥鸿药业有限责任公司 | 2019-09-17 | — | — | CN | claimed |
| CN-106660955-B | Cyclohexene derivative, preparation method and the pharmaceutical composition for being used to prevent or treat metabolic disease comprising it as active constituent | 现代药品株式会社 | 2019-08-23 | — | — | CN | claimed |
| CN-109942537-A | A kind of ALDH2 agonist, preparation method and its usage | 中国人民解放军第二军医大学 | 2019-06-28 | — | — | CN | claimed |
| CN-109942553-A | A kind of synthesis of tri- substituted-tetrahydro 2H- pyran-2-one compound of chirality 3,4,6- and its method for transformation | 大连理工大学 | 2019-06-28 | — | — | CN | claimed |
| CN-105980365-B | Benzimidazol-2-amines as mIDH1 inhibitors | 拜耳医药股份公司 | 2019-06-21 | — | — | CN | claimed |
| CN-109789645-A | Method for producing reinforced polyamides by extrusion | 巴斯夫欧洲公司 | 2019-05-21 | — | — | CN | claimed |
| CN-106674086-B | A kind of piperidones Alkaloid compound and its preparation method and application | 西安交通大学 | 2019-04-12 | — | — | CN | claimed |
| CN-109310668-A | Positive allosteric modulators of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2019-02-05 | — | — | CN | claimed |
| US-6150341-A | REACTING THE 5'OH GROUP OF VB12 OR AN ANALOGUE THEREOF WITH A BIFUNCTIONAL CARBONYL ELECTROPHILE TO FORM AN ACTIVE INTERMEDIATE, AND SUBSEQUENTLY REACTING THE INTERMEDIATE WITH A NUCLEOPHILIC SPACER MOLECULE TO YIELD VB12 DERIVATIVE | BIOTCH AUSTRALIA PTY LIMITED (AU) | 2000-11-21 | — | — | US | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999065930-A1 | VITAMIN B12 DERIVATIVES AND METHODS FOR THEIR PREPARATION | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 1999-12-23 | — | — | WO | claimed |
| US-5759727-A | TONER IMAGE ON TRANSPARENT SUBSTRATE; MELT POLYMER BACKING | XEROX CORPORATION (US) | 1998-06-02 | — | — | US | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0414009-A2 | Reduction of acidity of polyesters by melt reaction endcapping with dialkyloxalate | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-02-27 | — | — | EP | claimed |
| US-4983691-A | Reduction of acidity of polyesters by melt reaction endcapping with dialkyloxylate or tetraalkyl urea | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-01-08 | — | — | US | claimed |