Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264234 | 1.00 | GAA (0.31) | GAA | |
| SCHEMBL280345 | 0.83 | HRH2 (0.30) | GAA | |
| SCHEMBL263491 | 0.80 | MEN1 (0.31) | — | |
| SCHEMBL264088 | 0.80 | GRIA1 (0.33) | GAA | |
| SCHEMBL4818891 | 0.80 | GRIA1 (0.33) | GAA | |
| SCHEMBL264059 | 0.78 | CYP1A2 (0.32) | — | |
| SCHEMBL260423 | 0.78 | CYP1A2 (0.32) | — | |
| SCHEMBL2058918 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL260706 | 0.75 | ALDH1A1 (0.33) | GAA | |
| SCHEMBL260521 | 0.75 | HRH2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579477-B2 | Thiazole-based nitric oxide donors having alkyl substituent(s) and uses thereof | RENOPHARM LTD. (IL) | 2009-08-25 | — | — | US | claimed |
| US-7368577-B2 | Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof | RENOPHARM LTD. (IL) | 2008-05-06 | — | — | US | disclosed |