Iodofalan

Iodofalan

SCHEMBL44619

N[C@@H](Cc1ccc(I)cc1)C(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.69
PTGS1 P23219 3/20 0.68
ALPI P09923 1/20 0.68
PKM P14618 1/20 0.68
XIAP P98170 1/20 0.68
HIF1A Q16665 5/20 0.58
ALOX15 P16050 3/20 0.58
KDM4E B2RXH2 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
HSD17B10 Q99714 2/20 0.58
USP2 O75604 1/20 0.58
EGFR P00533 1/20 0.58
LCK P06239 1/20 0.58
FYN P06241 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
HTR2A P28223 1/20 0.58
PTGS2 P35354 1/20 0.58
RECQL P46063 1/20 0.58
TPH1 P17752 1/20 0.57
GRB2 P62993 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodofalan SCHEMBL44618 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Iodofalan SCHEMBL44620 1.00 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Iodofalan SCHEMBL23824892 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Iodofalan SCHEMBL3385531 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
Iodofalan SCHEMBL167365 0.98 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL31369954 0.94 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Fenclonine SCHEMBL8710394 0.91 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Iodofalan SCHEMBL28790138 0.90 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2310526 0.89 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL27898591 0.89 SLC7A5 (0.81) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6007 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12577575-B2 Methods and compositions for promoting non-natural amino acid-containing protein production AMBRX, INC. (US) 2026-03-17 US claimed
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-19 US claimed
EP-4689127-A1 RF1 KO E. COLI STRAINS Sutro Biopharma, Inc. (US) 2026-02-11 EP claimed
US-12540197-B2 Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates SUTRO BIOPHARMA, INC. (US) 2026-02-03 US claimed
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US claimed
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-11-06 US claimed
EP-4644570-A1 HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING BGI Shenzhen (CN) 2025-11-05 EP claimed
US-20250325633-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES Synthorx, Inc. (US) 2025-10-23 US claimed
US-20250325632-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES Synthorx, Inc. (US) 2025-10-23 US claimed
WO-1998037097-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES WAPHARM AB (SE) 1998-08-27 WO claimed
WO-1998012176-A1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS SYNPHAR LABORATORIES INC. (US) 1998-03-26 WO claimed
WO-1998006386-A2 DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM ROCHE DIAGNOSTICS GMBH (DE) 1998-02-19 WO claimed
US-5623049-A FLEXIBLE ANTISENSE AGENTS COMPRISING OLIGONUCEOTIDES HAVING THE (DEOXY)RIBOSE BACKBONE REPLACED BY AN OLIGOPEPTIDE; PROTEASE- AND NUCLEASE-RESISTANT; VIRICIDES; ATTACHED TO CARRIERS ABLE TO PENETRATATE IN CELLS BAYER AKTIENGESELLSCHAFT (DE) 1997-04-22 US claimed
EP-0700928-A1 Nucleic acid-binding oligomers for therapy and diagnostics BAYER AG (DE) 1996-03-13 EP claimed
US-5470830-A Motilin-like polypeptides that inhibit gastrointestinal motor activity OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1995-11-28 US claimed
US-5422341-A Antidiabetic agents OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1995-06-06 US claimed
EP-0647656-A1 Motilin-like polypeptides that inhibit gastrointestinal motor activity Ohmeda Pharmaceutical Products Division Inc. (US) 1995-04-12 EP claimed
EP-0646595-A1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1995-04-05 EP claimed
EP-0646601-A1 Motilin-like polypeptides with gastrointestinal motor stimulating activity Ohmeda Pharmaceutical Products Division Inc. (US) 1995-04-05 EP claimed