Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodofalan SCHEMBL44619 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Iodofalan SCHEMBL44620 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Iodofalan SCHEMBL44618 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Fenclonine SCHEMBL3140768 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Fenclonine SCHEMBL245828 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Fenclonine SCHEMBL26383 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Fenclonine SCHEMBL26382 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| Fenclonine SCHEMBL988270 | 0.90 | SLC7A5 (0.67) | SLC7A5PTGS1ALPIPKMXIAP | |
| Fenclonine SCHEMBL6357978 | 0.90 | SLC7A5 (0.67) | SLC7A5PTGS1ALPIPKMXIAP | |
| Fenclonine SCHEMBL16825893 | 0.90 | SLC7A5 (0.67) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807819-A | USING AN OLIGOPEPTIDE | LA JOLLA CANCER RESEARCH CENTER (US) | 1998-09-15 | — | — | US | disclosed |
| US-5792745-A | ADMINISTERING CYCLIC PEPTIDE HAVING GLYCINE-ASPARTIC ACID CORE SEQUENCE | LA JOLLA CANCER RESEARCH CENTER (US) | 1998-08-11 | — | — | US | disclosed |
| US-5773412-A | USING CYCLIC PEPTIDE | LA JOLLA CANCER RESEARCH CENTER (US) | 1998-06-30 | — | — | US | disclosed |
| US-5770565-A | AMINO ACID SEQUENCE CONSISTS OF ALTLEAST ONE ARGANINE-GLYCINE-ASPARTIC ACID SEQUENCE; INHIBIT BINDING OF OSTEOCLAST TO A MATRIX SUCH AS BONE | LA JOLLA CANCER RESEARCH CENTER (US) | 1998-06-23 | — | — | US | disclosed |
| US-5759996-A | REDUCE BONE RESORPTION, ANGIOGENESIS, AND RESTENOSIS | LA JOLLA CANCER RESEARCH CENTER (US) | 1998-06-02 | — | — | US | disclosed |