SCHEMBL4462382

SCHEMBL4462382

CC(C)(c1ccccc1)C(OP(O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.40
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
CYP3A4 P08684 1/20 0.36
KCNN4 O15554 4/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2C19 P33261 2/20 0.34
HIF1A Q16665 1/20 0.34
LMNA P02545 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11147173 0.85 ALDH1A1 (0.39) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL4462379 0.83 MAPK1 (0.43) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL18544240 0.77 ALDH1A1 (0.58) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL6809764 0.77 ALDH1A1 (0.46) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL11174553 0.74 ALDH1A1 (0.32) ALDH1A1ALOX15MAPK1KCNN4CYP2C19
SCHEMBL4462032 0.73 ALDH1A1 (0.43) ALDH1A1ALOX15MAPK1ESR1ESR2
Hydrogen Peroxide SCHEMBL27577220 0.72 ALDH1A1 (0.55) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL4448590 0.72 ALDH1A1 (0.42) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL29157603 0.72 ALDH1A1 (0.42) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL11403309 0.72 ALDH1A1 (0.31) ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed