Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471391 | 0.92 | TLR7 (0.61) | TLR7 | |
| SCHEMBL735484 | 0.92 | TLR7 (0.73) | TLR7 | |
| SCHEMBL1344514 | 0.91 | TLR7 (0.66) | TLR7 | |
| SCHEMBL4459360 | 0.90 | TLR7 (0.59) | TLR7 | |
| SCHEMBL4457533 | 0.90 | TLR7 (0.59) | TLR7 | |
| SCHEMBL9936854 | 0.90 | TLR7 (0.62) | TLR7 | |
| SCHEMBL4468070 | 0.90 | TLR7 (0.58) | TLR7 | |
| SCHEMBL4461136 | 0.89 | TLR7 (0.57) | TLR7 | |
| SCHEMBL4130549 | 0.89 | TLR7 (0.60) | TLR7 | |
| SCHEMBL4457492 | 0.89 | TLR7 (0.60) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041135-A1 | 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7 | Astra Zeneca AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008004948-A1 | 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7 | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |