Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130549 | 0.95 | TLR7 (0.60) | TLR7 | |
| SCHEMBL2862789 | 0.95 | TLR7 (0.60) | TLR7 | |
| SCHEMBL4132122 | 0.95 | TLR7 (0.60) | TLR7 | |
| SCHEMBL4138771 | 0.93 | TLR7 (0.60) | TLR7 | |
| SCHEMBL9971018 | 0.93 | TLR7 (0.73) | TLR7 | |
| SCHEMBL5530824 | 0.93 | TLR7 (0.60) | TLR7 | |
| SCHEMBL4126391 | 0.93 | TLR7 (0.60) | TLR7 | |
| SCHEMBL4131529 | 0.93 | TLR7 (0.66) | TLR7 | |
| SCHEMBL4132555 | 0.93 | TLR7 (0.63) | TLR7 | |
| SCHEMBL5524578 | 0.92 | TLR7 (0.61) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651943-B1 | PURINE DERIVATIVES | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-8895570-B2 | Purine derivatives | ASTRAZENECA AB (SE) | 2014-11-25 | — | — | US | disclosed |
| US-20130338174-A1 | PURINE DERIVATIVES | Sumitomo Pharma Co., Ltd. (JP) | 2013-12-19 | — | — | US | disclosed |
| EP-2651943-A1 | PURINE DERIVATIVES | Astrazeneca AB (SE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080730-A1 | PURINE DERIVATIVES | ASTRAZENECA AB (SE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338174-A1 | PURINE DERIVATIVES | HPRT1, PNP, SLC29A1 | TLR7 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.