Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL5707793 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHROPRM1 | |
| SCHEMBL7777186 | 0.91 | — | — | |
| SCHEMBL42985 | 0.91 | — | — | |
| Silicate SCHEMBL11801968 | 0.89 | ALDH1A1 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1465726 | 0.88 | — | — | |
| SCHEMBL2590479 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL2120477 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1465559 | 0.88 | — | — | |
| Alcohol SCHEMBL8633305 | 0.84 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| Alcohol SCHEMBL5181934 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135877-A1 | DIBLOCK COPOLYMER-SUBSTITUTED SUCCINIC ACID DERIVATIVES | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |
| EP-0582168-B1 | Use of intumescent carriers in fire-proof glasses | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| US-5328719-A | Reaction product of aluminum compound, phosphorus and boron containing acid and alkanolamine | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0582168-A1 | Use of intumescent carriers in fire-proof glasses | BAYER AG (DE) | 1994-02-09 | — | — | EP | disclosed |
| EP-0582167-A1 | Improved intumescent carriers and their use | BAYER AG (DE) | 1994-02-09 | — | — | EP | disclosed |
| US-4536448-A | ACRYLIC FIBER, HYDROXYETHYLAMMONIUM SALT OF A FATTY ESTER OR AMIDE | TOHO RAYON CO., LTD. | 1985-08-20 | — | — | US | disclosed |