SCHEMBL4462996

SCHEMBL4462996

Cc1c(C(=O)NNC(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.83

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 15/20 0.83
CNR1 P21554 6/20 0.78
PPARA Q07869 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31478247 1.00 CNR2 (0.83) CNR2CNR1PPARA
SCHEMBL4911796 0.90 CNR2 (0.81) CNR2CNR1
SCHEMBL4460349 0.89 CNR2 (0.77) CNR2CNR1PPARA
SCHEMBL2734336 0.88 CNR2 (0.83) CNR2CNR1PPARA
SCHEMBL16197644 0.88 CNR2 (0.76) CNR2CNR1PPARA
SCHEMBL924108 0.87 CNR2 (0.77) CNR2CNR1
SCHEMBL3130177 0.87 CNR2 (1.00) CNR2CNR1
SCHEMBL924033 0.87 CNR2 (0.76) CNR2CNR1PPARA
SCHEMBL30571219 0.87 CNR2 (0.76) CNR2CNR1PPARA
SCHEMBL4480064 0.87 CNR2 (0.77) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7632852-B2 (1,5-diphenyl-1H-pyrazol-3-yl)oxadiazole derivatives, preparation method thereof and use of same in therapeutics SANOFI-AVENTIS (FR) 2009-12-15 US disclosed
US-20080039510-A1 (1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXADIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2008-02-14 US disclosed
EP-1853595-A1 (1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXADIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2007-11-14 EP disclosed
WO-2006087480-A1 (1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXADIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2006-08-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080039510-A1 (1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXADIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS DHFR, DPYD, THPO CNR2 933/4885CNR1 767/4885PPARA 1910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.