SCHEMBL4463071

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4462769	0.90	CNR1 (0.57)	CNR1TSHRGAASMN1; SMN2KMT2A
	SCHEMBL4464050	0.89	CNR1 (0.69)	CNR1MAPTTSHRHTTGAA
	SCHEMBL4462150	0.88	CNR1 (0.50)	CNR1MAPTTSHRSMN1; SMN2KDM4E
	SCHEMBL4480861	0.79	CNR1 (1.00)	CNR1TSHRGAASMN1; SMN2HPGD
	SCHEMBL4456958	0.78	CNR1 (0.59)	CNR1TSHRKMT2AHPGD
	SCHEMBL4462594	0.78	CNR1 (1.00)	CNR1MAPTTSHRHTTKDM4E
	SCHEMBL14256885	0.77	CNR1 (0.54)	CNR1MAPTTSHRHTTGAA
	SCHEMBL4457216	0.76	CNR1 (0.53)	CNR1TSHRHTTSMN1; SMN2KDM4E
	SCHEMBL9142237	0.75	MAPT (0.38)	CNR1MAPTGAAKDM4EKMT2A
	SCHEMBL4467375	0.75	KDM4E (0.39)	CNR1MAPTTSHRHTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.