Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465585 | 1.00 | F10 (0.79) | F10AR | |
| SCHEMBL4461915 | 0.92 | F10 (0.65) | F10 | |
| SCHEMBL4473742 | 0.92 | F10 (0.65) | F10 | |
| SCHEMBL4475098 | 0.92 | F10 (0.77) | F10AR | |
| SCHEMBL4460992 | 0.88 | F10 (1.00) | F10AR | |
| SCHEMBL4459997 | 0.85 | F10 (0.78) | F10 | |
| SCHEMBL4467794 | 0.85 | F10 (0.78) | F10 | |
| SCHEMBL4475137 | 0.83 | F10 (0.64) | F10 | |
| SCHEMBL4459632 | 0.81 | F10 (0.86) | F10AR | |
| SCHEMBL4009887 | 0.81 | F10 (0.65) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476663-B2 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-13 | — | — | US | disclosed |
| US-20050277628-A1 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277628-A1 | Substituted thiophene carboxamides | OTC, SLC22A8, DDC | F10 2132/4885AR 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.