Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 7/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | CDC25B | P30305 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619268 | 0.90 | TSHR (0.75) | TSHRALDH1A1LMNAL3MBTL1AKR1C3 | |
| SCHEMBL195278 | 0.90 | TSHR (0.75) | TSHRALDH1A1LMNAL3MBTL1AKR1C3 | |
| SCHEMBL29121130 | 0.89 | TSHR (0.68) | TSHRALDH1A1LMNAL3MBTL1AKR1C3 | |
| SCHEMBL4733061 | 0.89 | TSHR (0.68) | TSHRALDH1A1LMNAL3MBTL1CDC25B | |
| SCHEMBL9356956 | 0.87 | TSHR (0.66) | TSHRALDH1A1LMNAL3MBTL1CDC25B | |
| SCHEMBL9379355 | 0.86 | TSHR (0.88) | TSHRALDH1A1LMNAL3MBTL1CDC25B | |
| SCHEMBL31009568 | 0.86 | TSHR (0.88) | TSHRALDH1A1LMNAL3MBTL1CDC25B | |
| Alcohol SCHEMBL11299285 | 0.84 | TSHR (0.62) | TSHRALDH1A1LMNAL3MBTL1AKR1C3 | |
| SCHEMBL7017547 | 0.84 | TSHR (0.62) | TSHRALDH1A1LMNAL3MBTL1CDC25B | |
| SCHEMBL7651252 | 0.84 | AKR1C3 (0.68) | ALDH1A1LMNAL3MBTL1AKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2495260-B2 | MANUFACTURING METHOD FOR PROPYLENE POLYMER | JAPAN POLYPROPYLENE CORP (JP) | 2018-10-24 | — | — | EP | disclosed |
| US-8957166-B2 | Method for producing propylene-based polymer | JAPAN POLYPROPYLENE CORPORATION (JP) | 2015-02-17 | — | — | US | disclosed |
| EP-2495260-B1 | MANUFACTURING METHOD FOR PROPYLENE POLYMER | JAPAN POLYPROPYLENE CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-20120302716-A1 | METHOD FOR PRODUCING PROPYLENE-BASED POLYMER | JAPAN POLYPROPYLENE CORPORATION (JP) | 2012-11-29 | — | — | US | disclosed |
| EP-2495260-A1 | MANUFACTURING METHOD FOR PROPYLENE POLYMER | Japan Polypropylene Corporation (JP) | 2012-09-05 | — | — | EP | disclosed |
| US-20090280977-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L (IT) | 2009-11-12 | — | — | US | disclosed |
| US-7276463-B2 | Polymerization catalyst for α-olefins and process for production of α-olefin polymers therewith | JAPAN POLYPROPYLENE CORPORATION (JP) | 2007-10-02 | — | — | US | disclosed |
| US-20060068984-A1 | Plymerization catalyst for a-olefins and process for production of alpha-olefin polymers therewith | JAPAN POLYCHEM CORPORATION (JP) | 2006-03-30 | — | — | US | disclosed |
| EP-1548035-A1 | CATALYST FOR POLYMERIZING a-OLEFIN AND PRODUCTION METHOD OF a-OLEFIN POLYMER USING THE SAME | Japan Polypropylene Corporation (JP) | 2005-06-29 | — | — | EP | disclosed |
| EP-0849291-B1 | Catalyst for olefin polymerization and method for preparing polyolefins | JAPAN POLYOLEFINS CO LTD (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5693729-A | STEREOSPECIFIC CATALYZING IN PRESENCE OF A MIXTURE CONSISTING OF A TITANIUM AND A MAGNESIUM COMPOUND, AN ORGANOALUMINUM COMPOUND OR AN ALUMOXANE, AN ORGANOSILICON COMPOUND | SHOWA DENKO K.K. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0578473-B1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KK (JP) | 1997-11-19 | — | — | EP | disclosed |
| EP-0640624-B1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KK (JP) | 1997-06-18 | — | — | EP | disclosed |
| EP-0773235-A1 | Polymerization of alpha-olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0717053-A2 | Catalyst for olefin polymerization and process for producing polyolefin using the same | JAPAN POLYOLEFINS CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0704424-A1 | 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5476825-A | Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound | SHOWA DENKO K.K. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5407883-A | Containing magnesium, titanium, aluminum and silicon compounds including polymeric aluminum and alumoxanes | SHOWA DENKO K.K. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0640624-A1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0578473-A1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-01-12 | — | — | EP | disclosed |